Trifluoroborates

BoroChem's product catalogue includes an important number of trifluoroborates. Click here to be redirected to an overview of available trifluoroborates.

Trifluoroborates are new classes of air-stable boronic acid derivatives that can be easily prepared and purified. Trifluoroborates offer a unique alternative to most boronic acids, esters and organoboranes for use in Suzuki-Miyaura and other transition-metal-catalyzed cross-coupling reactions, as described by Dr. Gary Molander.

The incompatibility of B-C bond with several oxidants limits the possibilities to further transformations of organoboron derivatives. Taking advantage of strong B-F bonds, the use of trifluoroborates may be viewed as a way to protect boron’s vacant orbital from an electrophilic reaction.

Advantages of trifluoroborates

• High air and moisture stability, increased stability to long-term storage
• Stable in water, water can be used as a solvent
• Low molecular weight
• Low toxicity and environmental impact, easy removal of inorganic by-products
  
  

Main benefits of the use of trifluoroborates in Suzuki-Miyaura cross-couplings

• Versatile reagents for Suzuki-Miyaura cross-coupling
• Easy cross-coupling in the presence of sensitive functional groups

BoroChem's product catalogue includes an important number of trifluoroborates. Click here to be redirected to an overview of available trifluoroborates.