Core technological expertise in boron-based compounds
BoroChem has unique know-how and technological expertise in the engineering and synthesis of boron-based compounds.
In our production process, we employ an innovating cryoboration technique, using temperatures from -40°C down to – 100°C, enabling to:
| • | better control reaction speed | | • | enhance specificity | | • | reduce unwanted side products |
Core competences
•
| Halogenations
| • Bromination (NBS, PBr3, Br2, …)
• Iodination (I2, …)
• Chlorination (POCl3, NCS, …)
| •
| Organometalic Chemistry
| • Halogen-Metal exchanges (BuLi, BuLi/amine, …)
• Directed metalations (LDA, LTMP, LiCKOR, …)
• Grignard | •
| Metal-catalysed cross coupling
| • Palladium catalysed Borylation
• Miyaura-Suzuki
• Negishi, Kumada, Heck, … | •
| Chemistry of boronopeptides
| • Protection / deprotection of amino-acids
• Synthesis of peptidomimetics | •
| Boronation of unprecedented heterocycles
| • Azaindole
• Furan
• Imidazole
• Indole
• Oxazole
• Pyrazole
• Pyridine
• Pyrimidine
• Pyrrole
• Quinoline
• Thiophene, ...
| •
| Miscellaneous
| • Matteson Homologation reaction
• Petasis reaction |
|
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